| CatalogCode: | | NB100-2143 |
| ProductName: | | CD11b Antibody |
| Product Description: | | Mouse Monoclonal anti-CD11b (OX42), conjugated to Biotin |
| Clone: | | OX42 |
| Clonality: | | Monoclonal |
| Immunogen: | | Rat peritoneal macrophages. |
| Specificity: | | This antibody recognizes the rat equivalent of human CD11b, the receptor for the iC3b component of complement. |
| CrossReactivity: | | Cross-reacts with Rat. Not yet tested in other species. |
| Packaging: | | 0.1 mg Mouse ascites. |
| Uses: | | FACS: label 106 cells in 100ul. IHC-P: has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde) (4). |
| Localization: | | Plasma membrane |
| Background: | | The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglial cells in the brain. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host_Name: | | Mouse |
| Buffer: | | 0.5% BSA, PBS. pH 7.2 |
| ListPrice: | | 285 |
| AppSummary: | | FACS, IHC-P |
| SpeciesSummary: | | Rt |
| ALTnames: | | anti-Cell Surface Glycoprotein MAC1 Alpha Subunit antibody, anti-Complement Component Receptor 3 Alpha antibody, anti-CR3A antibody, anti-ITGAM antibody, anti-MAC1A antibody, anti-MO1A antibody, anti-Neutrophil Adherence Receptor antibody |
| ProteinTarget: | | CD11b [OX42] |
| PackageSize: | | 0.1 mg |
| Conjugate: | | Biotin |
| GeneralRef: | | 1. Robinson, A.P. et al. (1986) Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognising complement receptor type 3. Immunology. 57(2): 239-247. 2. Barclay, A.N. (1981) The localization of population of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology. 42: 593-600. 3. Milligan, C.E. et al. (1991) Differential immunochemical markers reveal the normal distribution of brain macrophages and microglia in the developing rat brain. J. Comp. Neurol. 314: 125-135. 4. Whiteland, J.L. et al. (1995) Immunohistochemical detection of T cell Subsets and other leucocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J. Histochem. Cytochem. 43: 313-320. |
| more information: | | company product webpage |