| CatalogCode: | NB100-2138 |
| ProductName: | STAT6 Antibody |
| Product Description: | Rabbit Polyclonal anti-STAT6 [Tyr641] |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide of human STAT6 around Try641. |
| Specificity: | Detects a band at approximately 100kDa |
| CrossReactivity: | Human and Mouse. Not tested in any other species. |
| Packaging: | 0.1 mg |
| Uses: | ELISA: 0.1-1.0 ug/ml. IHC-P: 1/25 - 1/50 for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. The optimal dilution for a specific application should be determined by the investigator. Not tested in any other applications. |
| Localization: | Nuclear and cytoplasmic |
| Control: | Breast carcinoma |
| Background: | Stat6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. Stat6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. Stat6 is critically involved in Th2 immune response. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | IgG purified |
| Host_Name: | Rabbit |
| Buffer: | 10mM PBS, pH 7.4, with BSA and sodium azide |
| ListPrice: | 325 |
| AppSummary: | ELISA, IHC-P |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-STAT6 antibody, anti-STAT6C antibody, anti-D12S1644 antibody, anti-IL-4-STAT antibody, anti-interleukin 4 induced STATantibody |
| ProteinTarget: | STAT6 (Tyr641) |
| PackageSize: | 0.25 ml |
| Phosphorylated: | Tyr641 |
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