| Catalog Code: | NB100-2087 |
| Product Type: | Primary Antibody |
| Product Name: | Bcl-2 Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 596 |
| Host: | Mouse |
| Clone: | 124 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-Bcl-2 (124) |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | Bcl-2 is encoded by a gene involved in the 14; 18 chromosomal translocation. In lymphoid tissues, this antibody stains B lymphocytes as well as T cells. |
| Immunogen: | Recombinant Bcl-2 peptide sequence comprising 41 - 54 amino acids of Bcl-2 oncoprotein. |
| Localization: | Endoplasmic reticulum, Outer Mitochondrial membrane and Nuclear membrane |
| Purity: | Tissue culture supernatant |
| Buffer: | Preservative: Sodium Azide Constituents: Tissue Culture Supernatant |
| Packaging: | 250 microlitres Liquid. This antibody contains sodium azide as a preservative. |
| Package Size: | 0.25 ml |
| Uses: | Immunohistochemistry: use at a dilution of 1 / 15 - 1 / 50 for 30 - 60 mins at RT (ABC method). Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.This antibody works well with B5 or Bouin's fixed |
| Application Summary: | IHC-Fr, IHC-P |
| General References: | Hockenbery D et al. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-6 (1990). Tsujimoto Y & Croce CM Analysis of the structure, transcripts, and protein products of bcl-2, the gene involve |