| CatalogCode: | NB100-196 |
| ProductName: | RFXANK Antibody |
| Product Description: | Rabbit Polyclonal anti-RFXANK |
| Clonality: | Polyclonal |
| Immunogen: | Rabbits were immunized with a synthetic peptide between amino acids 425 and the c-terminus of RFXANK (human RFXANK entry sp O14593). After multiple immunizations in Freund's adjuvant, serum was collected. Antibodies were affinity purified using the peptide immobilized on solid support. |
| Specificity: | NB 100-196 reacts with RFXANK |
| CrossReactivity: | This antibody reacts with Homo sapiens. Other species have not been tested. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | Suggested working dilutions: *Western Blot 1:500 to 1:5,000Immunoprecipitation 1 to 4 ulImmunocytochemistry NDImmunohistochemistry ND*The investigator should determine the optimal dilution for a specific application.This antibody can be used for Western Blot and Immunoprecipitation. |
| Background: | MHC class II deficiency is an autosomal recessive immunodeficiency syndrome resulting from defects in transacting factors essential for transcription of MHC class II genes. There are 4 genetic complementation groups (A, B, C, and D), reflecting the existence of 4 MHC class II regulators. Group B is characterized by a defect in RFX binding, and although it accounts for the majority of patients, the factor defective in group B remained unknown until Masternak et al. (1998) isolated RFX by a novel single-step DNA-affinity purification approach and identified RFXANK, the gene encoding the third subunit of RFX. The gene was symbolized RFXANK because the protein contains 3 ankyrin repeats. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide |
| ListPrice: | 285 |
| AppSummary: | WB, IP |
| SpeciesSummary: | Hu |
| ALTnames: | anti-ANKRA1 antibody, anti-Ankyrin repeat containing regulatory factor X associated protein antibody, anti-BLS antibody, anti-DNA-binding protein RFXANK antibody, anti-Regulatory factor X associated ankyrin containing protein antibody, anti-Regulatory factor X subunit B antibody, anti-RFXB antibody, anti-RFXB delta 4 antibody |
| ProteinTarget: | Regulatory Factor X, Ankyrin Repeat-Containing (RFXANK) |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
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