| Catalog Code: | NB100-182 |
| Product Type: | Primary Antibody |
| Product Name: | Fanconi anemia D2 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 2177 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-Fanconi anemia D2 |
| Cross Reactivity: | NB 100-182 reacts with human and mouse FANCD2. |
| Species Summary: | Hu, Mu |
| Background: | Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellula |
| Alternate Names: | anti-FA4 antibody, anti-FACD antibody, anti-FAD antibody, anti-FAD2 antibody, anti-FANCD antibody, anti-Fanconi Anemia Complementation Group D antibody, anti-Fanconi Pancytopenia Type 4 antibody |
| Immunogen: | Human FANCD2 fusion protein (N-terminal fragment). |
| Specificity: | This antibody is specific for FANCD2. |
| Purity: | Affinity purified |
| Buffer: | PBS with 1% BSA |
| Packaging: | 0.05 ml of affinity purified rabbit antisera. |
| Package Size: | 0.05 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody can be used for Western analysis, immunohistochemistry, immunofluorescence, and immunoprecipitation. By Western blot, this antibody should recognize a band at ~166 kDa (post-translationally modified form). Additional bands may be seen at l |
| Application Summary: | IHC, IF, IP, WCE, WB |
| Product References: | 1. Bekker-Jensen, S., et al. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 173: 195-206 (2006) 2. Dunn, J., P., et al. Activation of the Fanconi Anemia/BRCA Pathway and Recombination R |
| Novus References: | 1. Garcia-Higuera, I., et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Molecular Cell. 7: 249-262 (2001) [Western blot, Immunofluorescence, human] 2. Taniguchi, T., et al. Disruption of the Fanconi anemia-BRCA pathway in |
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