| Catalog Code: | NB100-180SS |
| Product Type: | Primary Antibody |
| Product Name: | XRCC-3 Antibody |
| List Price: | 95 |
| Clonality: | Monoclonal |
| Gene ID: | 7517 |
| Host: | Mouse |
| Clone: | 10F1/6 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-XRCC-3 (10F1/6) **Sample Size** |
| Cross Reactivity: | Human XRCC3. Does not work in mouse. Other species not tested. NB 100-180 does not cross-react with Rad51B, Rad51C, Rad51D, Rad51, or XRCC2 in Western analysis. |
| Species Summary: | Hu, Mu(-) |
| Background: | Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross |
| Alternate Names: | anti-DNA repair protein XRCC3 antibody, anti-X ray repair complementing defective repair in Chinese hamster cells 3 antibody, anti-X ray repair cross complementing protein 3 antibody |
| Immunogen: | His-tagged human XRCC3, over-expressed in E. coli |
| Specificity: | This antibody is specific for XRCC3 |
| Purity: | protein A purified |
| Packaging: | 0.025 ml protein A purified Mouse ascites. |
| Package Size: | 0.025 ml |
| Concentration: | 1.3 mg/ml |
| Uses: | By Western blot, this antibody recognizes a band at ~38 kDa. |
| Application Summary: | IF, WB |
| General References: | 1. Schild, D., et al. Evidence for simultaneous protien imteractions between human Rad51 paralogs. J. Biol. Chem. 275(22):16443-9, 2000. [Human] 2. Brenneman, M.A., et al. XRCC3 is required for effiecient repair of chromosome breaks by homologus recomb |
| Novus References: | 1. Forget, AL. et al. XRCC3 is recruited to DNA double strand breaks early and independent of Rad51. J. of Cell. Biochem. 93: 429-436, 2004. <b>[<i>Immunofluorescence</i>]</b> 2. Fan, R., et al. Defective Strand Break Repair af |
| Notes Main: | **NOTE: This antibody's form has been changed. It is now sold in its purified form. All lots, other than lot A, have been purified. |
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