| CatalogCode: | NB100-1740 |
| ProductName: | G6PD Antibody |
| Product Description: | Rabbit Polyclonal anti-G6PD |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized maps to a region between residues 50 and 100 of human Glucose-6-Phosphate Dehydrogenase using the numbering given in entry NP_000393.2 (GeneID 2539). |
| CrossReactivity: | This antibody cross-reacts with human. Other species have not been tested. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. No other applications have been tested. Suggested working dilution: *Immunohistochemistry: 1:100-1:500 (FFPE sections)Epitope exposure is not recommended (citrate buffer may hinder staining). Likely to work with frozen sections.*The investigator should determine the optimal working dilution for a specific application. |
| Background: | This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 350 |
| AppSummary: | IHC |
| SpeciesSummary: | Hu |
| ALTnames: | anti-G6PD antibody, anti-G6PDH antibody, anti-Glucose-6-Phosphate Dehydragenase antibody |
| ProteinTarget: | G6PD |
| PackageSize: | 0.1 ml |
| Gene_Id: | 2539 |
| Omim_ID: | NB100-236 |
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