| CatalogCode: | NB100-1727 |
| ProductName: | AMPK alpha 1 Antibody |
| Product Description: | Rabbit Polyclonal anti-AMPK alpha 1 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized maps to a region between residues 350 and 400 of human 5'-AMP-activated Protein Kinase, catalytic Alpha-1 chain using the numbering given in entry BAA36547.1 (GeneID 5562). |
| CrossReactivity: | This antibody cross-reacts with human. Other species have not been tested. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. No other applications have been tested. Suggested working dilution: *Immunohistochemistry: 1:100-1:500 (FFPE sections)Epitope exposure is not recommended (citrate buffer may hinder staining). Likely to work with frozen sections.*The investigator should determine the optimal working dilution for a specific application. |
| Background: | Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA with 0.09% Sodium Azide |
| ListPrice: | 350 |
| AppSummary: | IHC |
| SpeciesSummary: | Hu |
| ALTnames: | anti-AMPK alpha 1 antibody, anti-AMPK antibody, anti-PRKAA1 antibody, anti-protein kinase AMP-activated antibody, anti-alpha 1 catalytic subunit antibody |
| ProteinTarget: | AMPK alpha-1 |
| PackageSize: | 0.1 ml |
| Gene_Id: | 552 |
| Omim_ID: | NB100-239 |
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