| CatalogCode: | | NB100-1692 |
| ProductName: | | Cdk 9 Antibody |
| Product Description: | | Rabbit Polyclonal anti-Cdk 9 |
| Clonality: | | Polyclonal |
| Immunogen: | | Multiple synthetic peptides corresponding to C-terminal and N-terminal domains of the protein coded by the human gene cdk9 (PITALRE) |
| Specificity: | | No reaction is observed against other related cyclin dependent kinases. |
| CrossReactivity: | | Cross-reacts with Human, Rat and Mouse.Not yet tested in other species. |
| Packaging: | | 0.1 ml Whole Rabbit antisera. |
| Uses: | | Predicted molecular weight: 43 kDa. |
| Localization: | | Nuclear |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Whole antisera |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | Whole sera, sterile filtered. |
| ListPrice: | | 325 |
| AppSummary: | | ELISA, IP, WB, IHC-P |
| SpeciesSummary: | | Hu, Mu, Rt |
| ALTnames: | | Anti-C 2k antibody; Anti-CDC2 related kinase antibody; Anti-CDC2L4 antibody; Anti-Cdk 9 antibody; Anti-Cell division cycle 2 like protein kinase 4 antibody; Anti-Cell division protein kinase 9 antibody; Anti-Cyclin dependent kinase 9 antibody; Anti-PITALRE antibody; Anti-Serine threonine protein kinase PITALRE antibody; Anti-TAK antibody |
| ProteinTarget: | | Cdk9 |
| PackageSize: | | 0.1 ml |
| GeneralRef: | | Bagella L <i>et al.</i> Cloning of murine CDK9/PITALRE and its tissue-specific expression in development. <i>J Cell Physiol</i> <b>177</b>:206-13 (1998). <PUBMED:9766517> de Falco G & Giordano A CDK9 (PITALRE): a multifunctional cdc2-related kinase. <i>J Cell Physiol</i> <b>177</b>:501-6 (1998). <PUBMED:10092203> Zhou Q <i>et al.</i> Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages. <i>EMBO J</i> <b>17</b>:3681-91 (1998). <PUBMED:9649438> Fujinaga K <i>et al.</i> The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat. <i>J Virol</i> <b>72</b>:7154-9 (1998). <PUBMED:9696809> Grana X <i>et al.</i> PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro. <i>Proc Natl Acad Sci U S A</i> <b>91</b>:3834-8 (1994). <PUBMED:8170997> |
| NotesMain: | | cdk9(PITALRE) interacts with a conserved domain in the TRAF-C region of the tumor necrosis factor signal transducer TRAF2. The positive transcription elongation factor b (P-TEFb) is identified as cdk9 paired with cyclin T1. |
| more information: | | company product webpage |