| CatalogCode: | NB100-1688 |
| ProductName: | Rb 2 Antibody |
| Product Description: | Rabbit Polyclonal anti-Rb 2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide (Human) conjugated to KLH. |
| Specificity: | No reaction is observed against other related tumor supressor proteins. |
| CrossReactivity: | Cross-reacts with Human, Rat and Mouse.Not yet tested in other species. |
| Packaging: | 0.1 ml Liquid |
| Uses: | ELISA (1:500 to 1:2000), immunoprecipitation, immunoblotting (1:500 to 1:1000), immunohistochemistry (1:200 to 1:1000)and other immunological methods requiring high titer and specificity. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Whole antisera |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 0.01M Na phosphate, 0.25M NaCl, pH7.6, 0.05% Na azide, 0.01% Thimerisol, 15mg/ml BSA |
| ListPrice: | 325 |
| AppSummary: | ELISA, IHC-P, IP, WB |
| SpeciesSummary: | Hu, Rt, Mu |
| ALTnames: | anti-Retinoblastoma-like protein 2 antibody, anti-130 kDa retinoblastoma-associated protein antibody, anti-PRB2 antibody, anti-P130 antibody, anti-RBR-2 antibody, anti-RBL2 antibody |
| ProteinTarget: | Rb2 |
| PackageSize: | 0.1 ml |
| GeneralRef: | General / background references:Pucci B et al. pRb2/p130 promotes radiation-induced cell death in the glioblastoma cell line HJC12 by p73 upregulation and Bcl-2 downregulation. Oncogene 21:5897-905 (2002). Claudio PP et al. p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. Cancer Res 54:5556-60 (1994). Yeung RS et al. The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19. Oncogene 8:3465-8 (1993). Mayol X et al. Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene 8:2561-6 (1993). |
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