| CatalogCode: | | NB100-1679 |
| ProductName: | | ATM Antibody |
| Product Description: | | Rabbit Polyclonal anti-ATM [Ser1981] |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide: CSLAFEEGSpQSTTISS, corresponding to amino acids 1974-1988 of ATM. |
| Specificity: | | NB 100-1679 is directed against human ATM kinase and can detect native and over-expressed proteins in various tissues and extracts. |
| CrossReactivity: | | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | | 0.05 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | | Western blot: Molecular weight: 350 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | | Nuclear. Also found in endocyticvesicles in association with beta adaptin. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | 0.02 M Potassium phosphate, 0.15 M sodium Chloride pH 7.2 |
| ListPrice: | | 295 |
| NovusRef: | | 1. Chu, Po-Chen., et al. Cell, Tumor, and Stem Cell Biology: Silencing of p29 Affects DNA Damage Responses with UV Irradiation. 66: 8484-8491, 2006. |
| AppSummary: | | IF, WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-AT complementation group A antibody; anti-AT complementation group C antibody; anti-AT complementation group D antibody; anti-AT complementation group E antibody; anti-AT mutated protein antibody; anti-AT1 antibody; anti-ATA antibody; anti-Ataxia telangiectasia gene mutated antibody |
| ProteinTarget: | | ATM Protein Kinase pS1981 |
| PackageSize: | | 0.05 mg |
| GeneralRef: | | Bakkenist CJ & Kastan MB DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499-506 (2003). |
| Phosphorylated: | | Ser1981 |
| more information: | | company product webpage |