| CatalogCode: | NB100-1663 |
| ProductName: | ABCA1 Antibody |
| Product Description: | Mouse Monoclonal anti-ABCA1 - Astrocyte Marker |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant fragment, corresponding to amino acids 1800-2260 of Human ABCA1. |
| CrossReactivity: | Cross-reacts with Human, Mouse and Chicken. Not yet tested in other species. |
| Packaging: | 0.1 mg Affinity purified Mouse ascites. |
| Uses: | WB: Predicted molecular weight: 254 kDa. |
| Background: | This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. |
| ProductRef: | 1. Li, T., Chen, W. and Chiang, J.Y.L. (2007) PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine, J. Lipid Res., 48, 373-384. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS. pH 7.4 |
| ListPrice: | 325 |
| NovusRef: | Li, Tiangang., et al. Manuscripts: PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine. 10.1194/jlr.M600282-JLR200, 2006. |
| AppSummary: | ELISA, IP, WB, IHC-P |
| SpeciesSummary: | Ch, Hu, Mu |
| ALTnames: | anti-ABC 1 antibody, anti-ABC Transporter 1 antibody, anti-ABC1 antibody, anti-ATP-binding Cassette 1 antibody, anti-ATP-binding Cassette Transporter 1 antibody, anti-CERP antibody, anti-Cholesterol Efflux Regulatory Protein antibody, anti-ABC-1 antibody |
| ProteinTarget: | ABCA1 |
| PackageSize: | 0.1 mg |
| Marker: | Astrocyte Marker |
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