| CatalogCode: | NB100-1660 |
| ProductName: | Kappa Opioid Receptor Antibody |
| Product Description: | Rabbit Polyclonal anti-Kappa Opioid Receptor |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: DPAYLRDIDGMNKPV, corresponding to amino acids 366-380 of Human Kappa Opioid Receptor. |
| CrossReactivity: | Cross-reacts with Human. Expected to cross-react with Mouse (86% identity with immunogen), Rat (86% identity with immunogen) and Guinea pig (93% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Packaging: | 0.5 ml |
| Uses: | ICC: Use at a dilution of 1/1000. IHC-Fr: Use at a dilution of 1/1000. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Plasma membrane |
| Background: | Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacologic studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Whole antisera |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: Whole Serum |
| ListPrice: | 285 |
| AppSummary: | ICC, IHC-Fr |
| SpeciesSummary: | Hu |
| ProteinTarget: | Kappa Opioid Receptor |
| PackageSize: | 0.05 ml |
| GeneralRef: | General / background references:Mansson E et al. Isolation of a human kappa opioid receptor cDNA from placenta. Biochem Biophys Res Commun 202:1431-7 (1994). |