| CatalogCode: | NB100-1638 |
| ProductName: | ATM Antibody |
| Product Description: | Rabbit Polyclonal anti-ATM |
| Clonality: | Polyclonal |
| Immunogen: | Recombinant fragment, corresponding to amino acids 1980-2338 of Human ATM. |
| CrossReactivity: | Cross-reacts with Human, Mouse, Hamster and Monkey. Not yet tested in other species. |
| Packaging: | 0.5 ml |
| Uses: | This antibody can be used in Immunohistochemistry and Western Blot. In Western Blot a 366.7 kDa band is seen. For IHC, perform heat mediated antigen retrieval before commencing with IHC staining protocol.This antibody is unsuitable for IHC on frozen sections or IP. |
| Localization: | Primarily nuclear. Found also in endocytic vesicles in association with beta Adaptin. |
| Background: | ATM protein is expressedwithin the nucleus ofall normal cells, and is thought to be important in detection of DNA damage. The ATM gene is defective in Ataxia telangiectasia. |
| Purity: | Whole antisera |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Whole Serum containing 0.09% sodium azide |
| ListPrice: | 285 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Ha, Hu, Mu, Mk |
| ALTnames: | anti-AT complementation group A antibody, anti-AT complementation group C antibody, anti-AT complementation group D antibody, anti-AT complementation group E antibody, anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxia telangiectasia gene mutated antibody |
| ProteinTarget: | ATM |
| PackageSize: | 0.05 ml |
| GeneralRef: | Lakin ND et al. Analysis of the ATM protein in wild-type and ataxia telangiectasia cells. Oncogene 13:2707-16 (1996). |
| NotesMain: | Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |