| CatalogCode: | NB100-1616 |
| ProductName: | PGP9.5 Antibody |
| Product Description: | Rabbit Polyclonal anti-PGP9.5 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: ASSEDTLLKDAAKVCR, corresponding to amino acids 176-191 of Human PGP9.5. |
| CrossReactivity: | Cross-reacts with Human, Mouse, Rat and Pig. Expected to cross-react with Horse (87% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.05 ml Whole antisera Rabbit antisera. |
| Uses: | In Western Blot a 26.8 kDa band is seenNot tested in other applications.*Optimal dilutions should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | PGP9.5 is a soluble cytoplasmic protein with a molecular weight of approximately 25,000 kD. It is present in neurons and in cells of the diffuse neuroendocrine system. PGP9.5 functions as a tissue-specific ubiquitin carboxyl terminal hydrolase isoenzyme. This enzyme is also known as UCH-L1. Because of its abundance in nerves, it has been widely used as a marker for peripheral nerve fibers |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Whole antisera |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Whole Serum |
| ListPrice: | 285 |
| AppSummary: | WB, IHC-Fr |
| SpeciesSummary: | Hu, Mu, Po, Rt |
| ALTnames: | anti-PGP9.5 antibody; anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1 antibody; anti-EC 3.4.19.12 antibody; anti-UCH-L1 antibody; anti-Ubiquitin thiolesterase L1 antibody; anti-Neuron cytoplasmic protein 9.5 antibody; anti-UCHL1 antibody |
| ProteinTarget: | PGP9.5 |
| PackageSize: | 0.05 ml |
| GeneralRef: | Navarro X et al. Immunohistochemical study of skin reinnervation by regenerative axons. J Comp Neurol 380:164-74 (1997). Day IN et al. The structure of the human gene encoding protein gene product 9.5 (PGP9.5), a neuron-specific ubiquitin C-terminal hydrolase. Biochem J 268:521-4 (1990). Doran JF et al. Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. J Neurochem 40:1542-7 (1983). |
| NotesMain: | Serum may become trapped in top of vial during shipping. Centrifugation of vial is recommended before opening. |