| CatalogCode: | NB100-1539 |
| ProductName: | NGFR Antibody |
| Product Description: | Goat Polyclonal anti-NGFR |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide with sequence C-AKREEVEKLLNG, representing the internal region of the human protein according to NP_002498.1 |
| Epitope: | internal region |
| Specificity: | This antibody is specific for NGFR |
| CrossReactivity: | Human, Mouse, Rat, Dog |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in ELISA and Western Blot where a 75kDa band has been observed in Human Duodenum and Human Heart lysates. Predicted MW is 45.2kDa according to NP_4804. The observed molecular weight corresponds to earlier findings in literature (Nykjaer et al, Curr Opin Neurobiol. 2005 Feb;15(1):49-57). Recommended dilutions: ELISA 1/32,000. WB: 0.3-1.0ug/ml. *Optimal dilutions should be determined by the end user. |
| Control: | also: MDA-MB-231 from Santa Cruz |
| Background: | Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. |
| ProductRef: | Nykjaer A, Willnow TE, Petersen CM. p75NTR--live or let die. Curr Opin Neurobiol. 2005 Feb;15(1):49-57. Review. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing 0.02% sodium azide, pH7.3 with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Ca, Hu, Mu, Rt |
| ALTnames: | anti-NGFR antibody, anti-nerve growth factor receptor (TNFR superfamily antibody, anti-member 16) antibody, anti-HGNC antibody, anti-7809 antibody, anti-TNFRSF16 antibody, anti-p75(NTR) antibody, anti-p75NTR antibody |
| ProteinTarget: | NGFR |
| Gene_Id: | 4804 |
| Omim_ID: | NB100-55851 |