| CatalogCode: | NB100-1529 |
| ProductName: | Neuroserpin Antibody |
| Product Description: | Goat Polyclonal anti-Neuroserpin |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide with sequence C-TMNTSGHDFEEL, representing the C Terminus of the human protein according to NP_005016.1 |
| Epitope: | C Terminus |
| Specificity: | This antibody is specific for Neuroserpin |
| CrossReactivity: | Human, Mouse, Rat, Chimpanzee |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in ELISA and Western Blot where a 48kDa band has been observed in Human Brain lysate. Predicted MW is 46.4kDa according to NP_005016.1). Recommended dilutions: ELISA 1/32,000. WB 1.0-3.0ug/ml. *Optiamal dilutions should be determined by the end user. |
| Background: | Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons (Stoeckli et al., 1989). It is expressed in the late stages of neurogenesis during the process of synapse formation.[supplied by OMIM] |
| ProductRef: | Onda M, Belorgey D, Sharp LK, Lomas DA. Latent Ser49Pro neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies. J Biol Chem. 2005 Jan 21; [Epub ahead of print] |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing 0.02% sodium azide, pH7.3 with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu, Mu, Rt, Mk |
| ALTnames: | anti-SERPINI1 antibody, anti-PI12 antibody, anti-neuroserpin antibody, anti-serine (or cysteine) proteinase inhibitor antibody, anti-clade I (neuroserpin) antibody, anti-member 1 antibody, anti-protease inhibitor 12 (neuroserpin) antibody |
| ProteinTarget: | Neuroserpin - Growth Cone |
| PackageSize: | 0.1 mg |
| Gene_Id: | 5274 |
| Omim_ID: | NB100-65478 |
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