| Catalog Code: | NB100-1513 |
| Product Type: | Primary Antibody |
| Product Name: | Bid Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 637 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-Bid |
| Cross Reactivity: | Reacts with Human and Mouse. Not yet tested in other species |
| Species Summary: | Hu |
| Background: | Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid transloca |
| Alternate Names: | anti-Apoptotic death agonist antibody, anti-Apoptotic death agonist BID antibody, anti-BH3 interacting domain death agonist antibody, anti-HGNC:1050 antibody, anti-Human BID coding sequence antibody |
| Immunogen: | Synthetic peptide C-TYVRSLARNGMD, representing the C-Terminus of the human protein, according to NP_932070.1; NP_001187.1; NP_932071.1. |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, approx 26+24kDa bands observed in Human fibroblast A431 lysates (calculated MW of 26.8kDa according to NP_932070.1 and 22.0kDa according to NP_001187.1). Not tested in other applicat |
| Application Summary: | ELISA, WB |
| General References: | Lund T, Stokke T, Olsen OE, Fodstad O. Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein Bim(EL) and induces apoptosis. Br J Cancer. 2005 Apr 12; [Epub ahead of print] PMID: 15827557 |