| CatalogCode: | NB100-1508 |
| ProductName: | ERK1 Antibody |
| Product Description: | Goat Polyclonal anti-ERK1 |
| Clonality: | Polyclonal |
| Immunogen: | Peptide with sequence GGEPRRTEGVGPC, from the N Terminus of the protein sequence according to NP_002737.1. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Suggested Starting Dilutions:*ELISA (peptide): detection limit dilution 1:4,000. Western Blot: 0.1-0.3ug/ml. ~45kDa band observed in Human Brain lysates, Kidney fibroblast HEK293 lysates and epidermoid fibroblast A431 lysates (calculated MW of 43.1kDa according to NP_002737.1).*Optimal dilutions/concentrations should be determined by the end user. |
| Background: | ERK1 is ubiquitously expressed in various tissues and cells. It is activated by phosphorylation of neighbouring serine and threonine residues by MEK1 and MEK2 in response to diverse stimuli such as growth factors and mitogens. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | unknown |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-MAPK3 antibody, anti-MAPK 1 antibodby, anti-p44-ERK1 antibody, anit-PRKM3 antibody |
| ProteinTarget: | ERK1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Wang PY, et al. OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation. Science 307(5714): 1472-6 (2005) PMID: 15746430 |
| Gene_Id: | 5595 |
| Omim_ID: | NB100-75588 |