| CatalogCode: | NB100-1500 |
| ProductName: | OSBP Antibody |
| Product Description: | Goat Polyclonal anti-OSBP |
| Clonality: | Polyclonal |
| Immunogen: | Peptide with sequence CKHQLEETKKEKRTRIP, from the Internal of the protein sequence according to NP_002547. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. Expected to react with dog, mouse, rat, rabbit and chimpanzee based on sequence similarity. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Suggested Starting Dilutions:*ELISA (peptide): detection limit dilution 1:32,000. Western Blot: 0.1-0.3ug/ml. ~85kDa band observed in Human Placenta lysates (calculated MW of 89.4kDa according to NP_002547). *Optimal dilutions/concentrations should be determined by the end user. |
| Background: | Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | unknown |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| NovusRef: | 1. Romeo GR, Kazlauskas A. Oxysterol and diabetes activate STAT3, and control endothelial expression of profilin-1 via OSBP1. J Biol Chem. 2008 January 28, 2008:M710092200. |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-OSBP 1 antibody, anti-OSBP antibody, anti-Oxysterol binding protein antibody, anti-Oxysterol binding protein 1 antibody |
| ProteinTarget: | OSBP |
| PackageSize: | 0.1 mg |
| GeneralRef: | Wang PY, et al. OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation. Science 307(5714): 1472-6 (2005) PMID: 15746430 |
| Gene_Id: | 5007 |
| Omim_ID: | NB100-1329 |
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