| CatalogCode: | NB100-1479 |
| ProductName: | VMAT2 Antibody |
| Product Description: | Goat Polyclonal anti-VMAT2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide C-SYPIGEDEESESD, representing the C-Terminus of the human protein (residues 502-514), according to NP_003045. |
| CrossReactivity: | Reacts with Human. Predicted to react with Rat (92% identity with immunogen) and Cow (92% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, a faint band of appr. 50kDa band observed in Human Placenta lysates (calculated MW of 55.7kDa according to NP_003045). Not tested in other applications.Recommended Starting Dilution:*ELISA (peptide): 1:8,000WB: 0.3-1.0 ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | VMAT2 (Vesicular amine transporter 2) acts to accumulate cytosolic monoamines into synaptic vesicles. Its function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders such as dementia with Lewy bodies. The transporter is a site of action of important drugs, including reserpine and tetrabenazine. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02 Na azide [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Slc18a2 antibody, anti-Solute carrier family 18 (vesicular monoamine) member 2 antibody, anti-SVAT antibody, anti-SVMT antibody, anti-Synaptic vesicle amine transporter brain antibody, anti-Synaptic vesicle monoamine transporter brain antibody, anti-VAT2 antibody, anti-Vesicular amine transporter 2 antibody, anti-Vesicular monoamine transporter 2 antibody, anti-VMAT2 antibody |
| ProteinTarget: | VMAT2 - Neuronal Marker |
| PackageSize: | 0.1 mg |
| GeneralRef: | Erickson JD et al. Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc Natl Acad Sci U S A 89:10993-7 (1992). PubMed: 1438304 |
| Gene_Id: | 6571 |
| Omim_ID: | NB100-63252 |
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