| Catalog Code: | NB100-1476 |
| Product Type: | Primary Antibody |
| Product Name: | PADI4 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 23569 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-PADI4 |
| Cross Reactivity: | Reacts with Human. Not yet tested in other species |
| Species Summary: | Hu |
| Background: | In vivo expression of PADI4 correlated with the appearance of citrulline in histones. We have shown that PADI4 converts arginines in the histone H3 tail to citrulline, that PADI4 blocks transcriptional activation and is recruited to the endogenous promoto |
| Alternate Names: | anti-EC 3.5.3.15 antibody, anti-HL 60 PAD antibody, anti-PADI5 antibody, anti-PDI5 antibody, anti-Peptidylarginine deiminase IV antibody, anti-Protein arginine deiminase type IV antibody |
| Immunogen: | Synthetic peptide AQGTLIRVTPEQPC, representing the N-Terminus of the human protein (residues 2-15), according to NP_036519. |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, approx 74kDa band observed in Human Spleen and Human Liver lysates (calculated MW of 74.1kDa according to NP_036519). Not tested in other applications. Recommended Starting Dilution:* |
| Application Summary: | ELISA, WB |
| General References: | Wang Y et al. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306:279-83 (2004). PubMed: 15345777 |