| Catalog Code: | NB100-147 |
| Product Type: | Primary Antibody |
| Product Name: | RAD50 Antibody |
| List Price: | 285 |
| Clonality: | Monoclonal |
| Gene ID: | 10111 |
| Host: | Mouse |
| Clone: | 13B3 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-RAD50 (13B3) |
| Cross Reactivity: | NB 100-147 reacts with human Rad50. |
| Species Summary: | Hu |
| Background: | Human Rad50, a 153kDa protein involved in DNA double strand break repair, is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co |
| Alternate Names: | anti-hRad50 antibody, anti-hsRad50 antibody, anti-Mrell antibody, anti-Rad50 2 antibody, anti-Rad50 homolog (S cerevisiae) antibody, anti-Rad50 PEN antibody, anti-Rad50l antibody, anti-Truncated Rad50 protein antibody |
| Immunogen: | Fusion protein containing the complete coding region (amino acids 1-425) of human Rad50, expressed in E. coli. |
| Localization: | Nuclear |
| Specificity: | This antibody is specific for Rad50. |
| Purity: | Tissue culture supernatant |
| Buffer: | PBS (pH7.4) |
| Packaging: | 0.1 ml Tissue culture supernatant Mouse ascites. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody is useful for Western blotting and immunofluorescence. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Novus References: | 1. Carbone, R., et al. PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage. Oncogene. 21: 1633-1640 (2002) 2. Evans, J. Distinct Roles of the Adenovirus E4 ORF3 Protein in Viral DNA Replication and Inhibition of Ge |
| Notes Main: | Hybridoma: Fusion between BALB/c splenocytes and mouse myeloma (NS-1 cells). |