| Catalog Code: | NB100-1465 |
| Product Type: | Primary Antibody |
| Product Name: | LXR alpha + LXR beta Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 10062 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-LXR alpha + LXR beta |
| Cross Reactivity: | Reacts with Human. Predicted to react with Mouse (100% identity with immunogen), Rat (100% identity with immunogen), Xenopus laevis (100% identity with immunogen), Zebrafish (100% identity with immunogen), Chicken (100% identity with immunogen), Cow (100% |
| Species Summary: | Hu |
| Background: | Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expresse |
| Alternate Names: | anti-Liver X receptor alpha antibody, anti-Liver X receptor beta antibody, anti-Nuclear receptor NER antibody, anti-Ubiquitously expressed nuclear receptor antibody, anti-LXR antibody, anti-LXRa antibody, anti-LXRb antibody, anti-NER antibody, anti-NERI a |
| Immunogen: | Synthetic peptide CRLQDKKLPPLLSEI, representing the C-Terminus of the human protein according to NP_005684; NP_009052. |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, approx 55kDa band observed in Human Spleen lysates (calculated MW of 50.5kDa according to NP_005684 and 50.1kDa according to NP_009052). Additional minor bands were also consistently o |
| Application Summary: | ELISA, WB |
| General References: | Tangirala RK et al. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proc Natl Acad Sci U S A 99:11896-901 (2002). PubMed: 12193651 |