| CatalogCode: | NB100-1440 |
| ProductName: | Bim Antibody |
| Product Description: | Goat Polyclonal anti-Bim |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: FNAYYARRLEK, representing the C-Terminus of the human protein (residues 159-169), according to NP_619528;NP_996886;NP_619529. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for Western Blot - detects a band of approximately 23 kDa (predicted molecular weight: 19, 9, 12 kDa). Not tested in other applications.Recommended Starting Dilution:*WB: 0.5 - 2 ug/ml*Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Intracytoplasmic membranes |
| Background: | Bim belongs to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide (pH7.3) with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-BAM antibody, anti-BCL2 interacting mediator of cell death antibody, anti-BCL2 interacting protein Bim antibody, anti-BCL2 like 11 apoptosis facilitator antibody, anti-BCL2 like protein 11 antibody, anti-BCL2 related ovarian death agonist antibody, anti-BCL2L11 antibody, anti-BIM antibody, anti-BimEL antibody, anti-BimL antibody, anti-BOD antibody |
| ProteinTarget: | Bim |
| PackageSize: | 0.1 mg |
| GeneralRef: | Marani M et al. Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis. Mol Cell Biol 22:3577-89 (2002). |
| Gene_Id: | 10018 |
| Omim_ID: | NB100-66059 |