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| Catalog Code: | NB100-1398 |
| Product Name: | SH3BP1 Antibody |
| Product Description: | Goat Polyclonal anti-SH3BP1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 23616 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide: PQPRPRSLASETN representing the C-Terminus of the human protein (residues 689-701) according to NP_061830. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA, Immunohistochemistry-Paraffinand and Western Blot. In WB detects a band of approximately 70 kDa (predicted molecular weight: 71 kDa) in human lung and kidney lysates (predicted MW of 71kDa according to NP_061830).Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Background: | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to c-Abl proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | ELISA 1:16,000, immunohistochemistry 0.3µg/ml, Western Blot 1-3µg/ml, Immunohistochemistry-Paraffin 0.3µg/ml |
| Species Summary: | Hu |
| Alternate Names: | anti-dJ37E16 antibody, anti-FLJ21318 antibody, anti-SH3-domain binding protein 1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | Dunham I et al. The DNA sequence of human chromosome 22. Nature 402:489-95 (1999). |
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