| CatalogCode: | NB100-1368 |
| ProductName: | EIF4ENIF1 Antibody |
| Product Description: | Goat Polyclonal anti-EIF4ENIF1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide AKVISVDELEYRQ, representing the C-Terminus of the human protein (residues 972-985) according to NP_062817. |
| CrossReactivity: | Cross-reacts with Human. Expected to cross-react with Mouse (100% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for Western Blot - detects a band of approximately 140-150 kDa (predicted molecular weight: 108 kDa according to NP_062817, however our observation agrees with that of Dostie et al.Not tested in other applications.Recommended Starting Dilution:*WB: 0.25 - 0.5 ug/ml*Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic;its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide (pH7.3) with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-2610509L04Rik antibody, anti-4E T antibody, anti-Clast4 antibody, anti-D11Ertd166e antibody, anti-eIF4E transporter antibody, anti-Eukaryotic translation initiation factor 4E nuclear import factor 1 antibody, anti-Eukaryotic translation initiation factor 4E transporter antibody, anti-FLJ21601 antibody |
| ProteinTarget: | EIF4ENIF1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Dostie J et al. A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E. EMBO J 19:3142-56 (2000). |
| NotesMain: | GenBank Accession Number ? NP_062817. |
| Gene_Id: | 56478 |
| Omim_ID: | H00056478-A01 |
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