| Catalog Code: | NB100-135 |
| Product Type: | Primary Antibody |
| Product Name: | AANAT Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 15 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-AANAT |
| Cross Reactivity: | Recognizes human, rhesus AANAT. It does not recognize rat, ovine, chicken or zebrafish AANAT. |
| Species Summary: | Hu, Mk, Rt(-), Ch(-), Ze(-), Bv(-) |
| Background: | Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function, and acts asthe hormone of the night. Large changes in the abundance of AANAT are b |
| Alternate Names: | anti-Arylalkamine N-Acetyltransferase antibody, anti-Serotonin-N-Acetyltransferase antibody |
| Immunogen: | Human AANAT |
| Specificity: | This antibody is specific for primate AANAT (3,4). |
| Packaging: | Immunopurified rabbit antiserum (100 ul). The peptide (hAANAT1-26) was bound to strips of PVDF membrane. The antiserum was eluted in 0.1N glacial acetic acid containing 0.1% BSA and neutralized using 10X PBS containing NaOH to a final pH of 6.8. |
| Package Size: | 0.1 ml |
| Uses: | By Western blot, this antibody recognizes a band at 23 kDa representing hAANAT. Suggested working dilutions: * Western Blot (ON at RT) 1:1,000 Western Blot (6 hr at RT)1:500 Immunocytochemistry ** *The investigator should determine the optimal working dil |
| Application Summary: | WB |
| Product References: | 1.Klein, D.C., Ganguly, S., Coon, S.L., Weller, J.L., Obsil, T., Hickman, A. and Dyda, F. (2002) 14-3-3 proteins and photoneuroendocrine transduction: Role in controlling the daily rhythm in melatonin. Biochem Soc Transactions. 30:365-372. 2.Iuvone, P.M |
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