| CatalogCode: | | NB100-1327 |
| ProductName: | | GRAF Antibody |
| Product Description: | | Goat Polyclonal anti-GRAF |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide KTGLIPENYVEFL, representing the C terminus of the human protein (residues 802-814)according to NP_055886. |
| CrossReactivity: | | Tested: Human Expected from sequence similarity: Mouse, Rat |
| Packaging: | | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | | Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 90kDa band observed in Human Heart lysates (calculated MW of 92.2kDa according to NP_055886.1). Recommended concentration: 0.3-1ug/ml. An additional strong band of unknown identity was also consistently observed at 16kDa. This band was successfully blocked by incubation with the immunising peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? |
| Background: | | GTPase regulator associated with the focal adhesion kinase pp125. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Goat |
| Buffer: | | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | | 295 |
| AppSummary: | | ELISA, WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-ARHGAP26 GTPase regulator associated with focal adhesion kinase pp125(FAK) antibody, anti-OPHN1L antibody, anti-Rho GTPase activating protein 26 antibody |
| ProteinTarget: | | GRAF |
| PackageSize: | | 0.1 mg |
| GeneralRef: | | Borkhardt A, Bojesen S, Haas OA, Fuchs U, Bartelheimer D, Loncarevic IF, Bohle RM, Harbott J, Repp R, Jaeger U, Viehmann S, Henn T, Korth P, Scharr D, Lampert F.The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9168-73. PMID: 10908648 |
| Gene_Id: | | 23092 |
| Omim_ID: | | NB100-75517 |
| more information: | | company product webpage |