| CatalogCode: | NB100-1292 |
| ProductName: | FBXL7 Antibody |
| Product Description: | Goat Polyclonal anti-FBXL7 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: CKRCVIEHTNPAFF representing the C-Terminus of the human protein (residues 478-491), according to NP_036436. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, dDetects a band of approximately 75 kDa(predicted molecular weight: 56 kDa). Please note that currently we cannot find an explanation in the literature for the band we observe given the predicted size of approx. 56KDa according to NP_036436. Not tested in other applications.Recommended Starting Dilution:*ELISA (peptide): 1/8000WB: 1ug*Optimal dilutions/concentrations should be determined by the end user. |
| Background: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. The F box, named after cyclin F in which it was originally observed, is an approximately 40-amino acid motif that binds SKP1. F-box proteins are components of modular E3 ubiquitin protein ligases called SCFs (SKP1, cullin, F-box proteins), which function in phosphorylation-dependent ubiquitination |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 195 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-F Box and Leucine Rich Repeat Protein 7 antibody, anti-FBL 6 antibody, anti-FBL 7 antibody, anti-FBL6 antibody, anti-FBL7 antibody, anti-FBXL 7 antibody, anti-FLJ11609 antibody, anti-KIAA0840 antibody |
| ProteinTarget: | FBXL7 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Cenciarelli C et al. Identification of a family of human F-box proteins. Curr Biol 9:1177-9 (1999). |
| NotesMain: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. |
| Gene_Id: | 23194 |
| Omim_ID: | H00023194-A01 |
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