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| Catalog Code: | NB100-1276 |
| Product Name: | ARH Antibody |
| Product Description: | Goat Polyclonal anti-ARH |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 26119 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide: DALKSAGRALIRS, representing the N-Terminus of the human protein (residues 9-21), according to NP_056442. |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse and Xenopus laevis due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for Western Blot - detects a band of approximately 40-45 kDa (predicted molecular weight: 35 kDa). Not tested in other applications.Recommended Starting Dilution:*WB: 1 - 3 ug/ml*Optimal dilutions/concentrations should be determined by the end user. |
| Background: | The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Application Summary: | Western Blot 1 - 3 ug/ml |
| Species Summary: | Hu, Mu, Xp, |
| Alternate Names: | anti-ARH antibody, anti-ARH2 antibody, anti-FHCB1 antibody, anti-FHCB2 antibody, anti-MGC34705 antibody, anti-DKFZp586D0624 antibody, anti-LDL receptor adaptor protein antibody, anti-LDLRAP1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% Na azide |
| General References: | He G et al. ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. J Biol Chem 277:44044-9 (2002). |
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more information: | company product webpage |