| Catalog Code: | NB100-1259 |
| Product Type: | Primary Antibody |
| Product Name: | ECT 2 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 1894 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-ECT 2 |
| Cross Reactivity: | Expected to cross-react with Human due to sequence homology. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phase |
| Alternate Names: | anti-Epithelial Cell Transforming Sequence 2 antibody, anti-ECT2 antibody |
| Immunogen: | Synthetic peptide: AENSVLTSTTGRT representing the N-Terminus of the human protein (residues 2-14), according to NP_060568. |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution >1:32,000.Western Blot: 100kDa band reported in human U87-MG glioblastoma lysate at 2.5ug/ml. A 30kDa band of unknown identity was also observed. |
| Application Summary: | ELISA, WB |
| General References: | Tatsumoto T et al. Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis. J Cell Biol 147:921-8 (1999). |
| Notes Main: | Gene Ontology terms - guanyl-nucleotide exchange factor activity; cell growth and/or maintenance; intracellular signaling cascade; intracellular. |