| CatalogCode: | NB100-1237 |
| ProductName: | GPS 1 Antibody |
| Product Description: | Goat Polyclonal anti-GPS 1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: PANSQSRMSTNM representing the C-Terminus of the human protein (residues 480-491), according to NP_004118. |
| CrossReactivity: | Cross-reacts with Human. Expected to cross-react with Mouse and Rat due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, detects a band of approximately 55 kDa (predicted molecular weight: 58 kDa according to NP_004118). Not tested in other applications.Recommended Starting Dilution:*ELISA (peptide): 1/32000WB: 0.5 ug/ml*Optimal dilutions/concentrations should be determined by the end user. |
| Background: | This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-COPS1 antibody, anti-CSN1 antibody, anti-MGC71287 antibody |
| ProteinTarget: | GPS 1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Spain BH et al. Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells. Mol Cell Biol 16:6698-706 (1996). |
| NotesMain: | GenBank Accession Number ? NP_004118.Gene Ontology terms - GTPase inhibitor activity; JNK cascade; inactivation of MAPK; cell cycle. LocusLink ID - 2873 (human); 209318 (mouse); 117039 (rat). |
| Gene_Id: | 2873 |
| Omim_ID: | H00002873-M01 |
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