| CatalogCode: | NB100-1128 |
| ProductName: | RAD51L1 Antibody |
| Product Description: | Goat Polyclonal anti-RAD51L1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide GSKKLKRVGLSQE, representing the N-Terminus of the human protein (residues 2-14), according to NP_002868; NP_598193; NP_598194 |
| Specificity: | This antibody is expected to recognise all three human isoforms. |
| CrossReactivity: | Expected to cross-react with Human due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, no signal obtained yet but low background observed in HeLa and Human Heart lysates. Not tested in other applications. Recommended Starting Dilution:*ELISA (peptide): 1:8,000)WB 1.0 ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. This protein is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 195 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-DNA repair protein RAD51 homolog 2 antibody, anti-hREC2 antibody, anti-R51H2 antibody, anti-RAD51 homolog B antibody, anti-REC2 antibody, anti-RecA-like protein antibody, anti-recombination repair protein antibody |
| ProteinTarget: | RAD51L1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Albala JS et al. Identification of a novel human RAD51 homolog, RAD51B. Genomics 46:476-9 (1997). |
| NotesMain: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. |
| Gene_Id: | 5890 |
| Omim_ID: | H00005890-B01 |
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