| CatalogCode: | | NB100-1087 |
| ProductName: | | CABP Antibody |
| Product Description: | | Goat Polyclonal anti-CABP |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic peptide GNCVKYPLRNLS, representing the N-Terminus of the human protein (residues 2-13), according to NP_004267; NP_112482 |
| Specificity: | | This antibody is expected to recognise both isoforms. |
| CrossReactivity: | | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | | This antibody can be used for Western Blot ? Approx 20kDa band seen in Human Brain lysate (predicted MW 19kDa). Not tested in other applications.Recommended Starting Dilution:*WB: 0.5-2.0ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | | The protein belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This protein is only detected in retina and brain. Study of the mouse homolog demonstrated that groups of cells expressing this protein are located in the center or inner border of the inner unclear layer of retina. Two alternatively spliced variants encoding different isoforms have been described. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgG |
| Host_Name: | | Goat |
| Buffer: | | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | | 295 |
| AppSummary: | | WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-CABP1 antibody, anti-CALBRAIN antibody, anti-Calcium binding protein 1 antibody, anti-Calcium binding protein 5 antibody, anti-HCALB_BR antibody |
| ProteinTarget: | | CABP |
| PackageSize: | | 0.1 mg |
| GeneralRef: | | Yamaguchi K et al. Calbrain, a novel two EF-hand calcium-binding protein that suppresses Ca2+/calmodulin-dependent protein kinase II activity in the brain. J Biol Chem 274:3610-6 (1999). |
| Gene_Id: | | 9478 |
| Omim_ID: | | NB100-75599 |
| more information: | | company product webpage |