| Catalog Code: | NB100-1076 |
| Product Type: | Primary Antibody |
| Product Name: | SF3B4 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 10262 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-SF3B4 |
| Cross Reactivity: | Cross-reacts with Human.Expected to cross-react with Mouse (100% identity with immunogen), Xenopus laevis (100% identity with immunogen), Zebrafish (100% identity with immunogen) and Drosophilia melanogaster (100% identity with immunogen) due to sequence |
| Species Summary: | Hu |
| Background: | The SF3B4 gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be i |
| Alternate Names: | anti-SAP49 antibody, anti-Spliceosomal protein antibody, anti-Spliceosome-associated protein (U2 snRNP) antibody, anti-Splicing factor 3b subunit 4 antibody |
| Immunogen: | Synthetic peptide: AAGPISERNQDAT, representing the N-Terminus of the human protein (residues 2-14), according to NP_005841. |
| Localization: | Nuclear |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, detects a band of approximately 50 kDa (predicted molecular weight: 49 kDa) in Hela lysate. Not tested in other applications. Recommended Starting Dilution:* ELISA: 1/16000 WB: 0.5 - |
| Application Summary: | ELISA, WB |
| General References: | Champion-Arnaud P & Reed R The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. Genes Dev 8:1974-83 (1994). |