| Catalog Code: | NB100-1060 |
| Product Type: | Primary Antibody |
| Product Name: | Plakoglobin Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 3728 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-Plakoglobin |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse (100% identity with immunogen), Rat (92% identity with immunogen), Cow (92% identity with immunogen) and Pig (92% identity with immunogen) due to sequence homology. Not yet tested in other specie |
| Species Summary: | Hu |
| Background: | Plakoglobin is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of |
| Alternate Names: | anti-Desmoplakin III antibody, anti-DP3 antibody, anti-DPIII antibody, anti-Gamma catenin antibody, anti-Junction plakoglobin antibody, anti-PDGB antibody, anti-PKGB antibody |
| Immunogen: | Synthetic peptide: GLRPPYPTADHMLA, representing the C-Terminus of the human protein (residues 730-743), according to NP_002221, NP_068831. |
| Localization: | Cytoplasmic in a soluble and membrane-associated form. |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, detects a band of approximately 85 kDa (predicted molecular weight: 86 kDa) in A431 lysate. Not tested in other applications. Recommended Starting Dilution:* ELISA: 1/32000 WB: 0.2 - |
| Application Summary: | ELISA, WB |
| General References: | Knudsen KA & Wheelock MJ Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin. J Cell Biol 118:671-9 (1992). |