| Catalog Code: | NB100-105SS |
| Product Type: | Primary Antibody |
| Product Name: | HIF-1 alpha Antibody |
| List Price: | 55 |
| Clonality: | Monoclonal |
| Gene ID: | 3091 |
| Host: | Mouse |
| Clone: | H1alpha67 |
| Isotype: | IgG2b |
| Product Description: | Mouse Monoclonal anti-HIF-1 alpha (H1alpha67) **Sample Size** |
| Cross Reactivity: | Human, monkey, sheep, mouse, rat, rabbit, pig, bovine and ferret HIF-1alpha. Other species have not been tested. |
| Species Summary: | Bv, Hu, Mu, Po, Mk, Rt, Rb, Ft, Sh |
| Background: | Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-1 is a nucle |
| Alternate Names: | anti-Hypoxia-inducible factor 1 alpha antibody, anti-HIF1 alpha antibody, anti-ARNT interacting protein antibody, anti-Hif1a antibody, anti-ARNT interacting protein antibody, anti-HIF-1alpha antibody, anti-Hypoxia inducible factor 1 alpha antibody, anti-H |
| Immunogen: | A fusion protein containing residues 432-528 of human HIF-1 alpha. |
| Localization: | Nuclear |
| Purity: | protein G purified |
| Buffer: | PBS |
| Packaging: | 0.025 ml protein G purified Mouse ascites. |
| Package Size: | 0.025 ml |
| Concentration: | 1.3 mg/ml |
| Uses: | By Western blot, this antibody recognizes bands at 120 kDa representing HIF-1 alpha in induced tissues and cells. Multiple bands may be seen at 120 kDa representing post-translational modification of HIF-1 alpha. This antibody has also been used to immuno |
| Application Summary: | IHC, IP, WB |
| Novus References: | 1. Alberghini, A., et al. (2005) J. Biol. Chem. 280(34): 30120-30128. [Western blot, Human] 2. Aminova, L.R., et al. (2005) J. Biol. Chem. 280(5): 3996-4003. [Western blot, Mouse] 3. Asikainen, T. M., et al. (2006) FASEB J. 20: 1698-1700. 4. Bateman, R. M |
| Notes Main: | Lot S is 1.3 mg/ml* The mobility of HIF-1 alpha induced by desferrioxamine or cobalt chloride treatment differs from the mobility of the hypoxia-induced protein. The reason is not known. |
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