| Catalog Code: | NB100-103 |
| Product Type: | Primary Antibody |
| Product Name: | Ku80 Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 7520 |
| Host: | Mouse |
| Clone: | 5D5.8 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-Ku80 (5D5.8) |
| Cross Reactivity: | Human. Other species have not been tested. |
| Species Summary: | Hu |
| Background: | Eukaryotic cells contain an abundant nuclear protein, Ku, which was initially discovered as an autoantigen. Ku is a heterodimer of 70 and 80 kDa subunits which binds to DNA ends and other alterations in double-stranded DNA including hairpins, nicks and g |
| Alternate Names: | anti-ATP dependent DNA helicase II 80 kDa subunit antibody, anti-ATP dependent DNA helicase II 86 Kd subunit antibody, anti-CTC box binding factor 85 kDa antibody, anti-CTC85 antibody, anti-CTCBF antibody, anti-DNA repair protein XRCC5 antibody, anti-KARP |
| Immunogen: | HeLa whole cell extracts |
| Specificity: | This antibody is specific for Ku 85 subunit. |
| Purity: | Affinity purified |
| Buffer: | PBS with 0.05% Sodium Azide |
| Packaging: | 0.25 ml of Protein G purified mouse ascites [0.2 mg/ml] in PBS with 0.05% sodium azide. |
| Package Size: | 0.25 ml |
| Uses: | A band at ~85 kD should be seen in Western analysis. Suggested working dilutions: * Western blot: 1/500 Other applications have not been tested. *The investigator should determine the optimal working dilution for a specific application. |
| Application Summary: | WB |
| General References: | 1. Dr. Stuart Linn, University of California at Berkeley, unpublished results 2. D. T. Weaver. What to do at an end: DNA double-strand-break repair. Trends in Genetics, 11(10): 388-392, 1995. 3. Robinson. The Ku Autoantigen: Cast in a New Light. Can |