| CatalogCode: | NB100-1011 |
| ProductName: | AXIN 1 Antibody |
| Product Description: | Goat Polyclonal anti-AXIN 1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide FEEKIIGKVEKVD, representing the C-Terminus of the human protein (residues 850-862), according to NP_003493; NP_851393. |
| CrossReactivity: | Expected to cross-react with Human, Mouse and Rat due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used for ELISA and Western Blot. In Western Blot, no signal obtained yet but low background observed in Human Brain, Human Pancreas, MOLT-4 and HeLa lysates. Not tested in other applications.Recommended Starting Dilution:*ELISA (peptide): 1:32000WB: 2.0ug/ml*Optimal dilutions should be determined by the end user. |
| Background: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. Negative regulator of Wnt signaling. Also associated with cancer. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing [pH7.3] with 0.5% BSA |
| ListPrice: | 195 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-AXIN1 antibody, anti-AXIN antibody, anti-MGC52315 antibody, anti-axin 1 antibody, anti-axis inhibitor 1 antibody, anti-fused antibody, anti-mouse antibody, anti-homolog of antibody, anti-axis inhibition protein 1 Official Gene Symbol - AXIN1GenBank Accession Number ? NP_003493 antibody, anti-NP_851393 LocusLink ID - 8312 (human) antibody, anti-12005 (mouse) antibody, anti-79257 (rat)Gene Ontology terms - signal transducer activity antibody, anti-oocyte axis determination antibody, anti-frizzled receptor signaling pathway antibody, anti-development antibody, anti-apoptosis antibody, anti-cytoplasm antibody, anti-negative regulation of cell cycle antibody, anti-Axis Inhibitor 1 antibody, anti-MGC52315 antibody |
| ProteinTarget: | AXIN 1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Zeng L et al. The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell 90:181-92 (1997). |
| NotesMain: | Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. |
| Gene_Id: | 8312 |
| Omim_ID: | H00008312-M01 |
|