| CatalogCode: | H00025836-M01 |
| ProductName: | NIPBL Antibody |
| Product Description: | Mouse Monoclonal anti-NIPBL (3B9) |
| Clone: | 3B9 |
| Clonality: | Monoclonal |
| Immunogen: | NIPBL (AAH33847, 66 a.a. ~ 175 a.a) partial recombinant protein with GST tag. |
| Epitope: | FHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGVRRRRSQRISQRIT ... |
| Specificity: | NIPBL - Nipped-B homolog (Drosophila) |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg IgG purified Mouse ascites. |
| Uses: | Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Background: | This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG2a Kappa |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CDLS antibody, anti-DKFZp434L1319 antibody, anti-FLJ11203 antibody, anti-FLJ12597 antibody, anti-FLJ13354 antibody, anti-FLJ13648 antibody, anti-FLJ44854 antibody, anti-IDN3 antibody, anti-IDN3-B antibody |
| ProteinTarget: | NIPBL - Nipped-B homolog (Drosophila) |
| PackageSize: | 0.1 mg |
| NotesMain: | This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours. The immunizing protein is also available for this product. Unit cost for the protein is $ 250 (2 ug). $ 305 (10 ug). and $ 445 (25 ug). |
| Gene_Id: | 25836 |
| Gene_Symbol: | NIPBL |
| Omim_ID: | 122470, 608667, |
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