| Catalog Code: | H00010818-M01 |
| Product Type: | Primary Antibody |
| Product Name: | FRS2 Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 10818 |
| Host: | Mouse |
| Clone: | 1F7-1D6 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-FRS2 (1F7-1D6) |
| Cross Reactivity: | Human. Other species not tested. |
| Species Summary: | Hu |
| Background: | NCBI Entrez Gene ID = FRS2 PLEASE NOTE - This product originates in Taiwan. If in stock in Taiwan, delivery is 10-14 days. If not in stock, lead times can be extended. We will inform you of any extended delays within 48 hours. |
| Alternate Names: | anti-FRS2A antibody, anti-FRS2alpha antibody, anti-SNT antibody, anti-SNT-1 antibody, anti-SNT1 antibody |
| Immunogen: | FRS2 (AAH21562, 1 a.a. ~ 513 a.a) full length recombinant protein with GST tag. |
| Epitope: | MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGP ... |
| Specificity: | FRS2 - fibroblast growth factor receptor substrate 2 |
| Purity: | IgG purified |
| Packaging: | 100 ug purified IgG |
| Package Size: | 0.1 ml |
| Uses: | Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Application Summary: | ELISA, WB |
| Product References: | Krejci P, Wilcox WR et al.. Bisindolylmaleimide I suppresses FGF-mediated activation of ERK map kinase in chondrocytes by preventing SHP2 association with the FRS2 and GAB1 adaptor proteins. J Biol Chem. 2007 Feb 2;282(5):2929-36. Epub 2006 Dec 4. |
| Notes Main: | This antibody is available only in North America and is supplied by Abnova The immunizing protein is also available for this product. Unit cost for the protein is $ 235 (2 ug), $ 285 (10 ug), and $ 425 (25 ug). |
| Gene Symbol: | FRS2 |
| Omim ID: | 607743 |