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| Catalog Code: | H00010540-B01 |
| Product Name: | DCTN2 Antibody |
| Product Description: | Mouse Polyclonal anti-DCTN2 - dynactin 2 (p50), MaxPab Antibody |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 10540 |
| Gene Symbol: | DCTN2 |
| Immunogen: | DCTN2 (AAH00718, 1 a.a. ~ 401 a.a) full-length human protein. |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. |
| Uses: | Antibody reactive against transfected lysate and tissue lysate for Western Blot. Has also been used for ELISA and immunofluorescence. |
| Background: | This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Host Name: | Mouse |
| Application Summary: | ELISA, immunofluorescence, Western Blot, |
| Species Summary: | Hu |
| Alternate Names: | anti-DCTN50 antibody, anti-DYNAMITIN antibody, anti-RBP50 antibody |
| Package Size: | 0.05 ml |
| Preservative: | No Preservative |
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more information: | company product webpage |