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| Catalog Code: | H00007402-A01 |
| Product Name: | UTRN Antibody |
| Product Description: | Mouse Polyclonal anti-UTRN |
| Clonality: | Polyclonal |
| ListPrice: | 225 |
| Gene ID: | 7402 |
| Gene Symbol: | UTRN |
| Omim ID: | 128240 |
| Immunogen: | UTRN (NP_009055, 3328 a.a. ~ 3434 a.a) partial recombinant protein with GST tag. |
| Epitope: | LEARMQILEDHNKQLESQLHRLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTST
DLTEVMEQIHSTFPSCCPNVPSRPQAM* |
| Specificity: | UTRN - utrophin (homologous to dystrophin) |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | The quality control of this antibody is limited to Western blot on the immunizing protein. <br>Abnovas recommended working dilutions for western analysis are as follows:<br>1:500 dilution for ascites<br>1:1000 for purified Ig<br>1:500-1:1000 for polysera |
| Background: | This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-DMDL antibody, anti-DRP antibody, anti-DRP1 antibody, anti-FLJ23678 antibody |
| Package Size: | 0.05 ml |
| Preservative: | No preservative |
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more information: | company product webpage |