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| Catalog Code: | H00007318-A01 |
| Product Name: | UBE1L Antibody |
| Product Description: | Mouse Polyclonal anti-UBE1L |
| Clonality: | Polyclonal |
| ListPrice: | 225 |
| Gene ID: | 7318 |
| Gene Symbol: | UBE1L |
| Omim ID: | 191325 |
| Immunogen: | UBE1L (NP_003326, 914 a.a. ~ 1013 a.a) partial recombinant protein with GST tag. |
| Epitope: | WDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVL
ELSCEGDDEDTAFPPLHYEL* |
| Specificity: | UBE1L - ubiquitin-activating enzyme E1-like |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | The quality control of this antibody is limited to Western blot on the immunizing protein. Abnovas recommended working dilutions for western analysis are as follows:1:500 dilution for ascites1:1000 for purified Ig1:500-1:1000 for polysera |
| Background: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-D8 antibody, anti-MGC12713 antibody, anti-UBE2 antibody |
| Package Size: | 0.05 ml |
| Preservative: | No preservative |
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more information: | company product webpage |