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| Catalog Code: | H00007170-A01 |
| Product Name: | TPM3 Antibody |
| Product Description: | Mouse Polyclonal anti-TPM3 |
| Clonality: | Polyclonal |
| ListPrice: | 225 |
| Gene ID: | 7170 |
| Gene Symbol: | TPM3 |
| Omim ID: | 161800 191030 |
| Immunogen: | TPM3 (AAH15403, 1 a.a. ~ 249 a.a) full length recombinant protein with GST tag. |
| Specificity: | TPM3 - tropomyosin 3 |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA. |
| Background: | This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-MGC72094 antibody, anti-NEM1 antibody, anti-TRK antibody |
| Package Size: | 0.05 ml |
| Preservative: | No preservative |
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more information: | company product webpage |