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| Catalog Code: | H00007077-M04J |
| Product Name: | TIMP metallopeptidase inhibitor 2 Antibody |
| Product Description: | Mouse Monoclonal anti-TIMP metallopeptidase inhibitor 2 (5B11) |
| Clone: | 5B11 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Gene ID: | 7077 |
| Gene Symbol: | TIMP2 |
| Omim ID: | 188825, |
| Immunogen: | TIMP2 (AAH52605, 27 a.a. ~ 221 a.a) full length recombinant protein with GST tag. |
| Specificity: | TIMP metallopeptidase inhibitor 2 |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg IgG purified Mouse ascites. |
| Uses: | Antibody reactive against recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA. |
| Background: | This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG2a Kappa |
| Host Name: | Mouse |
| Buffer: | 1X PBS pH 7.2 |
| Application Summary: | ELISA, immunofluorescence, Immunohistochemistry-Paraffin, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-CSC-21K antibody |
| Package Size: | 0.1 mg |
| Preservative: | No preservative |
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