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| Catalog Code: | H00006833-A01 |
| Product Name: | ABCC8 Antibody |
| Product Description: | Mouse Polyclonal anti-ABCC8 |
| Clonality: | Polyclonal |
| ListPrice: | 225 |
| Gene ID: | 6833 |
| Gene Symbol: | ABCC8 |
| Omim ID: | 125853 240800 256450 600509 |
| Immunogen: | ABCC8 (NP_000343, 611 a.a. ~ 711 a.a) partial recombinant protein with GST tag. |
| Epitope: | SEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWT
PDGIPTLSNITIRIPRGQLTM* |
| Specificity: | ABCC8 - ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | The quality control of this antibody is limited to Western blot on the immunizing protein. Abnovas recommended working dilutions for western analysis are as follows:1:500 dilution for ascites1:1000 for purified Ig1:500-1:1000 for polysera |
| Background: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-ABC36 antibody, anti-HI antibody, anti-HRINS antibody, anti-MRP8 antibody, anti-PHHI antibody, anti-SUR antibody, anti-SUR1 antibody |
| Package Size: | 0.05 ml |
| Preservative: | No preservative |
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more information: | company product webpage |