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| Catalog Code: | H00006776-A01 |
| Product Name: | STAT5A Antibody |
| Product Description: | Mouse Polyclonal anti-STAT5A |
| Clonality: | Polyclonal |
| ListPrice: | 225 |
| Gene ID: | 6776 |
| Gene Symbol: | STAT5A |
| Omim ID: | 601511 |
| Immunogen: | STAT5A (AAH27036, 1 a.a. ~ 104 a.a) partial recombinant protein with GST tag. |
| Epitope: | MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGED
GFLLKIKLGHYATQLQKTYDRCPLE |
| Specificity: | STAT5A - signal transducer and activator of transcription 5A |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. No preservative. |
| Uses: | The quality control of this antibody is limited to Western blot on the immunizing protein. Abnovas recommended working dilutions for western analysis are as follows:1:500 dilution for ascites1:1000 for purified Ig1:500-1:1000 for polysera |
| Background: | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host Name: | Mouse |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-MGF antibody, anti-STAT5 antibody |
| Package Size: | 0.05 ml |
| Preservative: | No preservative |
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more information: | company product webpage |