| CatalogCode: | H00004938-B01 |
| ProductName: | OAS1 Antibody |
| Product Description: | Mouse Polyclonal anti-OAS1 - 2',5'-oligoadenylate synthetase 1, 40/46kDa, MaxPab Antibody |
| Clonality: | Polyclonal |
| Immunogen: | OAS1 (AAH00562, 1 a.a. ~ 364 a.a) full-length human protein. |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.05 ml of mouse antisera with 50% glycerol. |
| Uses: | Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. |
| Background: | This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | WB, ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-IFI-4 antibody, anti-OIAS antibody, anti-OIASI antibody |
| ProteinTarget: | 2',5'-oligoadenylate synthetase 1, 40/46kDa |
| PackageSize: | 0.05 ml |
| NotesMain: | This antibody is available only in North America and is supplied by Abnova. Lead time may be 10-14 days. The immunizing protein may also available for this product. Unit cost for the protein is $250 (2 ug), $305 (10 ug), and $445 (25 ug). MaxPab is a registered trademark of Abnova. |
| Gene_Id: | 4938 |
| Gene_Symbol: | OAS1 |
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